Condition Guide

Dengue Fever

Dengue is a viral illness spread by Aedes mosquitoes. Knowing the warning signs and understanding your blood test results, especially platelet count, can be life-saving.

Written by Suman Konda, PharmD, Clinical Pharmacist · Based on peer-reviewed sources · Editorial policy · Not medical advice

Last updated: · How we check our content

What is dengue fever?

Dengue fever is a mosquito-borne viral infection caused by the dengue virus (DENV), transmitted by Aedes aegypti and Aedes albopictus mosquitoes. An estimated 390 million infections occur worldwide each year, of which around 96 million produce clinical illness, primarily in tropical and subtropical regions. Most cases cause a self-limiting febrile illness lasting 5–7 days. A small proportion progress to severe dengue (dengue haemorrhagic fever or dengue shock syndrome), which can be life-threatening without prompt hospital care.

Symptoms of dengue fever

Symptoms typically appear 4–10 days after a mosquito bite and include:

  • Sudden high fever (39–40°C / 102–104°F)
  • Severe headache, especially behind the eyes
  • Intense muscle and joint pain ("breakbone fever")
  • Skin rash: appears 2–5 days after fever starts
  • Nausea and vomiting
  • Fatigue and general weakness
  • Mild bleeding: nose bleeds, gum bleeding, easy bruising

⚠ Warning signs: go to hospital immediately

  • Severe abdominal pain or tenderness
  • Persistent vomiting (3+ times in 24 hours)
  • Bleeding from gums, nose or in vomit/stool
  • Rapid breathing or difficulty breathing
  • Feeling very restless, confused or drowsy
  • Platelet count below 20,000/µL

Dengue blood tests explained

TestWhen to useWhat it detects
NS1 AntigenDay 1–5 of feverDengue virus protein: best early test
IgM antibodyDay 5 onwardsRecent dengue infection
IgG antibodySecondary infectionsPast dengue exposure
CBC (Platelet count)Daily monitoringFalling platelets = dengue progression
Haematocrit (PCV)Daily monitoringRising haematocrit = plasma leakage (danger sign)

Platelet count in dengue

Platelet CountWhat it meansAction
> 100,000/µLMild dropMonitor daily, rest at home if no warning signs
50,000–100,000/µLModerate dropHospital assessment recommended
20,000–50,000/µLSevere dropHospital admission required
< 20,000/µLCriticalPlatelet transfusion may be needed

What to do if you have dengue

  • Rest: Complete bed rest is essential during the febrile phase
  • Hydration: Drink at least 2–3 litres of fluids daily, oral rehydration salts (ORS), coconut water, clear broth, fruit juices
  • Paracetamol only: Take paracetamol (acetaminophen) for fever and pain, do NOT take ibuprofen, aspirin or diclofenac (they increase bleeding risk)
  • Monitor platelet count: Daily CBC from day 3 of fever
  • Watch for warning signs: Go to hospital immediately if any danger signs appear
  • Mosquito control: Use mosquito nets and repellent to prevent spreading dengue to others

There is no specific antiviral treatment for dengue

Treatment is supportive: managing fever, maintaining hydration and monitoring for complications. Dengue vaccines exist (Dengvaxia) but are only approved for people with previous dengue infection. Research into better vaccines continues. Prevention through mosquito control remains the most important public health tool.

Questions to ask your doctor

  • Should I be admitted to hospital with this platelet count?
  • How often should I recheck my CBC?
  • When is it safe to return to work or school?
  • Can I give dengue to family members at home?

References

The clinical information on this page is based on peer-reviewed sources indexed in PubMed, the biomedical literature database of the US National Library of Medicine.

  1. Bhatt S, Gething PW, Brady OJ, et al. The global distribution and burden of dengue. Nature. 2013;496(7446):504-7. doi:10.1038/nature12060 · PMID 23563266

Related reading

Medical Disclaimer: This page is for general educational purposes only and does not constitute medical advice. Dengue can be life-threatening, always seek immediate medical attention if you suspect dengue or have any warning signs.